Key Summary
We have summarized 3,004 Rejuran reviews by Gangnam Unni and Babitalk where the products are Healer, Eye, and HB. Healer was used for the entire face and for dryness, elasticity, and pore problems. Rejuran I was used for wrinkles and dark circles in the eye area. HB was used for dryness and the entire face. The biggest difference in the reviews was pain.
- The positive-review rate was 94% (447 cases) for Healer, 90% (301 cases) for HB, and 80% (202 cases) for Rejuran I. Since the Rejuran I is a review of the eye area, the concerns are different, so it is not compared on the same line as the healer.
- Reviews that said it was quite painful were 24% for Healer, 25% for Rejuran I, and 4% for HB, and 61% for HB had the highest number of reviews that said it was almost no pain. The average for the injection bumps to subside was 2.0 days for Healer, 1.9 days for HB, and 1.5 days for Rejuran I.
- The cost was the lowest for Healer based on the same 1cc (approximately 146,000 won), Rejuran I was approximately 157,000 won, and HB Plus was approximately 173,000 won. The average cost for 2cc Healer is approximately 252,000 won.
90% of the 950 reviews about the effect said it was good, but 99% of the reviews were written within a month after the procedure, so it is impossible to know from the reviews how long the effect lasts.
What kind of product is Rejuran Healer, I, HB?
In the reviews, there were many posts saying that Healer received 2cc or 4cc for the entire face, Rejuran I received 1cc for the eye area, and HB (HB Plus) was a pain-reducing product that received 1cc to 4cc. Clinic information and articles explain that HB is a product that adds hyaluronic acid and anesthetic ingredients to Healer, but the pain reduction rate of HB varies from 50% to 70% in each article, so this article compares the pain rate written in the reviews.
| Product | Number of reviews | Areas frequently written in reviews | Capacity received a lot from reviews |
|---|---|---|---|
| Healer | 1,198 cases | Whole face, cheeks, eye area | 72 cases of 4cc, 57 cases of 2cc |
| Rejuran I | 938 cases | eye area 627 cases | 15 cases of 2cc, 10 cases of 1cc |
| HB | 868 cases | Lips, cheeks, entire face, eye area | 42 cases of 2cc, 41 cases of 4cc, 19 cases of 3cc |
The number of reviews for each product is the result of randomly selecting up to 1,000 reviews for each product, so it is not the actual usage rate. The reviews using the capacity were 137 for Healer, 27 for Rejuran I, and 117 for HB.
What are the most common concerns that come up in Rejuran reviews?
Healer and HB had the most dry skin (Healer 45%, HB 44%), while the Rejuran I had 51% wrinkles and 20% dark circles.
| Product | Most commonly used concerns (number of reviews) |
|---|---|
| Healer | 537 cases of dryness, 131 cases of dullness, 124 cases of wrinkles, 118 cases of elasticity, 117 cases of pores |
| Rejuran I | 483 wrinkles, 185 dark circles, 82 elasticity, 78 dryness |
| HB | 384 cases of dryness, 134 cases of wrinkles, 89 cases of pores, 88 cases of dullness, 82 cases of skin texture |
In Rejuran I, 67% (627 out of 938) of the reviews were about the eye area. If there are multiple concerns in one review, I wrote them down individually.
What was the effect of each product?
Out of 950 reviews of the effect, 90% said it was good, 94% of healers, 90% of HB, and 80% of Rejuran I. The reviews that said it was average were 3% of healers, 7% of HB, and 10% of Rejuran I, and the reviews that said it was ineffective were 3% of healers, 4% of HB, and 10% of Rejuran I.
| Product | Reviews with effects | Good review | Normal | There was no effect | When the effect was felt |
|---|---|---|---|---|---|
| Healer | 447 cases | 94% | 3% | 3% | Average 1.1 weeks (63 cases) |
| HB | 301 cases | 90% | 7% | 4% | Average 1.3 weeks (52 cases) |
| Rejuran I | 202 cases | 80% | 10% | 10% | Average 0.7 weeks (10 cases) |
By number of times it was received, Healer said it was good 96% (57 cases) once, 97% (37 cases) twice, and 87% (38 cases) three times or more, while for HB it was 82% (34 cases) once, 90% (31 cases) twice, and 89% (35 cases) three times or more. 76% (25 cases) of Rejuran I had it once, 61% (18 cases) twice, and 69% (36 cases) three or more times. I can't tell from the reviews whether the number of reviews received more for a reason.
How much does each product hurt?
Reviews that said it was quite painful were 24% of healers, 25% of Rejuran I, and 4% of HB, and reviews that said it was almost painful were 61% of HB, 43% of healers, and 36% of Rejuran I.
| Product | Number of reviews | It almost didn't hurt | It was bearable | It was quite painful |
|---|---|---|---|---|
| Healer | 475 cases | 43% | 33% | 24% |
| Rejuran I | 395 cases | 36% | 38% | 25% |
| HB | 492 cases | 61% | 35% | 4% |
Anesthesia was different for each product. For Healer, there were 180 cases of sedation, 82 cases of topical anesthetic cream, and 70 cases of local anesthesia, for Rejuran I, 110 cases of topical anesthetic cream, 29 cases of sedation, and 12 cases of local anesthesia, and for HB, 110 cases of topical anesthetic cream, 54 cases of local anesthesia, and 5 cases of sedation. Healer reviews often use sedation, so the pain rate is mixed with the influence of the anesthesia method.
How long do injection bumps and bruising last?
The average for injection bumps to subside was 2.0 days (70 cases) for healers, 1.9 days (91 cases) for HB, and 1.5 days (54 cases) for Rejuran I. Of the reviews that reported bruising, 64% (94 out of 146) were Rejuran I, 53% (42 out of 79) were HB, and 53% (42 out of 79) were Rejuran I among those who wrote about bruising. It was 50% (49 out of 98).
For Rejuran I who received it in the eye area, there were 66 reviews (7.0%) about swelling, which was more than the 18 reviews (1.5%) for Healer and 27 reviews (3.1%) for HB.
How many times do you get Rejuran and what are the intervals?
The average number of reviews was 2.1 for Healer (316), 2.1 for Ai (246), and 2.0 for HB (248), and the average interval was 5.5 to 6.0 weeks.
| Product | average number of times | average interval |
|---|---|---|
| Healer | 2.1 times (316 cases) | 6.0 weeks (70 cases) |
| Rejuran I | 2.1 times (246 cases) | 6.0 weeks (47 cases) |
| HB | 2.0 times (248 cases) | 5.5 weeks (53 cases) |
Most of the reviews were written right after the procedure, so they do not include the number of times I will receive them in the future.
What was the inconvenience behind Rejuran?
Of the 3,004 reviews, the most common discomfort was pain (165 for Healer, 151 for Rejuran I, 48 for HB), and Rejuran I also reported bruising (95) and swelling (66).
| Reported inconvenience | Healer (1,198 cases) | Rejuran I (938 cases) | HB (868 cases) |
|---|---|---|---|
| pain | 165 cases (13.8%) | 151 cases (16.1%) | 48 cases (5.5%) |
| injection bumps | 55 cases (4.6%) | 43 cases (4.6%) | 42 cases (4.8%) |
| bruising | 45 cases (3.8%) | 95 cases (10.1%) | 41 cases (4.7%) |
| swelling | 18 cases (1.5%) | 66 cases (7.0%) | 27 cases (3.1%) |
| blushing | 20 cases (1.7%) | 11 cases (1.2%) | 17 cases (2.0%) |
Only 28 (2.3%) healers, 23 (2.5%) Rejuran I, and 18 (2.1%) HB wrote reviews that they regretted or did not recommend. There were 1 to 2 cases of lumps and 0 to 2 cases of allergic reactions, but the rates were not small due to the low number of reviews.
How much is Rejuran?
The average price of the same 1cc disclosed by clinics was about 146,000 won for healer (11 places), about 157,000 won for Rejuran I (44 clinics), and about 173,000 won for HB plus (14 clinics), 2cc healer was about 252,000 won (76 clinics), and 4cc was about 430,000 won (7 places).
| Products and Capacity | Average per session | range | number of places | Average per 1cc |
|---|---|---|---|---|
| Healer 1cc | Approximately 146,000 won | 80,000 won to 330,000 won | 11 places | Approximately 146,000 won |
| Healer 2cc | Approximately 252,000 won | 142,000 won to 539,000 won | 76 clinics | Approximately 126,000 won |
| Healer 4cc | Approximately 430,000 won | 330,000 won to 550,000 won | 7 places | Approximately 107,000 won |
| Rejuran I 1cc | Approximately 157,000 won | 87,000 won to 330,000 won | 44 clinics | Approximately 157,000 won |
| HB Plus 1cc | Approximately 173,000 won | 119,000 won to 220,000 won | 14 clinics | Approximately 173,000 won |
Gangnam Unni sale price includes VAT and is the lowest price per clinic. First visit, experience, event, sedation, and package products were excluded. Configurations with less than 3 sites (2cc for Rejuran I, 2cc for HB or more) were not averaged. In many configurations, the larger the capacity, the lower the price per 1cc.
| Product | Number of reviews | Average price per time written in reviews |
|---|---|---|
| Healer | 641 cases | Approximately 299,000 won |
| HB | 402 cases | Approximately 277,000 won |
| Rejuran I | 395 cases | Approximately 127,000 won |
Looking at reviews based on capacity, Healer 2cc was about 264,000 won (28 reviews), 4cc was about 377,000 won (34 reviews), HB 2cc was about 271,000 won (16 reviews), and 4cc was about 406,000 won (17 reviews). The price in the review is the payment amount written on the platform, so it is not the same standard as the clinic's published price because it is a mix of dose, anesthesia, and concurrent procedures.
How was polynucleotide injection viewed in the study?
Several studies have shown that polynucleotide (PN) injections improve wrinkles, skin texture, and elasticity, and the side effects were mild and temporary, but the evidence is still based on small studies. The study below is not a comparison of Healer, Ai, and HB, but covers PN injections in general.
| Research | target | Results |
|---|---|---|
| Lampridou S et al., J Cosmet Dermatol 2025 | PN Study Part 9, Review of 219 People | Results with improved wrinkles, skin texture, and elasticity, as well as minor, temporary side effects. Because the procedures varied, there was no consensus on optimal use, and the quality of the studies was low to moderate. |
| Lee YJ et al., J Dermatolog Treat 2022 | eye area comparison of half faces of 27 people, 3 times at 2-week intervals | The wrinkle score was the same as that of hyaluronic acid filler, and the elasticity, moisture, roughness, and pore volume improvement rates were higher with PN. |
| Choi SY et al., J Cosmet Dermatol 2025 | Comparison of half faces of 218 people with eye area wrinkles, 12 weeks | PCL filler was not inferior to PN (Rejuran), and adverse reactions were mild for both. |
| Jeon W et al., Aesthetic Plast Surg 2026 | Comparison of half faces of 15 people | PN with adjusted pH and ionic strength had a pain score of 3.4 out of 10, which was lower than the existing PN's 5.0, and injection bumps were 13.3% vs. 56.7%. |
| Rho NK et al., Clin Cosmet Investig Dermatol 2026 | Expert opinion paper | It is used for moisturizing, rejuvenation, barrier recovery, and scar improvement. There were no reports of granulomas or vascular occlusion in the literature, but the evidence was summarized as limited. |
Jeon's research and reviews agree that pain and injection bumps are the most common inconveniences from PN injections. There is no independent paper in PubMed that directly compares the pain reduction rate of HB, so it is shown as the pain rate of the later period.
What product had a high positive-review rate in DermaFocus' Rejuran reviews?
Based on reviews, the products with the highest positive-review rates were Healer (94%) and HB (90%), and the product with the least pain was HB (quite painful, 4%). The Rejuran I review was 80% for the eye area, but it is not compared on the same level as Healer.
The products with the most reviews according to my concerns are as follows.
| Concerns written in reviews | Products with the most reviews | positive-review rate (effective reviews) | It was quite painful | Same 1cc public price |
|---|---|---|---|---|
| Full face dryness, elasticity, pores | Healer | 94% (447 cases) | 24% | Approximately 146,000 won |
| Dryness causing pain, entire face | HB | 90% (301 cases) | 4% | Approximately 173,000 won |
| eye area wrinkles, dark circles | Rejuran I | 80% (202 cases) | 25% | Approximately 157,000 won |
- 94% of healer reviews said the effect was good, but 24% said it was quite painful. There were many reviews using sedation, and the average injection bumps were 2.0 days.
- HB had the fewest reviews at 4% saying that it was quite painful, and the positive-review rate was 90%. The published price based on the same 1cc was about 27,000 won higher than Healer.
- 80% of Rejuran I's reviews said the eye area was good, but there were more reviews about bruising (10.1%) and swelling (7.0%) than other products. Injection bumps were the shortest, averaging 1.5 days.
There are other configurations that have good reviews. Reviews for Healer 1 and 2 times were 96% and 97% (57, 37), and reviews for HB 2 or more times were 89% to 90% (66).
Although 90% of the reviews that wrote about the effect said it was good, most of them were written immediately after the procedure. This comparison is based on reviews, not medical superiority or inferiority, and the results of the procedure vary from person to person, so the ratio of reviews does not guarantee the results. During the consultation, please confirm the area of concern, dosage, pain, anesthesia method, and the exact name of the product (Healer, Eye, HB, HB Plus).
What should I ask during a Rejuran consultation?
Start by asking which product you will receive: Healer, Eye, or HB (HB Plus) and how many cc. Even though it is called the same name in the reviews, the capacity and product are different.
| What to check | Questions to Ask |
|---|---|
| Products and Capacity | What is healer, Rejuran I, HB and how many cc? Can you confirm that the product has been opened? |
| part | Is it the entire face or just the eye area? Which product is right for my problem area? |
| Anesthesia and Pain | Is it numbing cream or sedation? How much does it hurt? Will the pain decrease if I switch to HB? |
| injection bumps and bruising | How many days do injection bumps last? How long does bruising and swelling last in the eye area? |
| Count and Interval | How many times will I receive it, and how many weeks apart will I receive it? |
| price | Is it a one-time amount or a total package amount? Are anesthesia and VAT included? What is the price per 1cc? |
| Actual practitioner | Does the doctor I consult perform the procedure themselves? |
DermaFocus compares Rejuran clinics like this
The recommendation guide applies the same four criteria to all clinics.
| Comparison Items | Verification criteria |
|---|---|
| Treatment information | Product (Healer, i, HB) and dosage information, frequency and interval, and whether or not information will be disclosed in case of side effects |
| medical staff | Specialist qualifications and actual practitioners confirmed by official sources |
| cost | Confirmation date, VAT, price conditions, dosage and whether anesthesia is included |
| Reviews | Repeated mention of sources, writing time, consultation and explanation for each platform |
The number of reviews and specialist qualifications are not used as scores to guarantee treatment results. The role of a recommendation guide is to display confirmed facts side by side using the same standards.
How this article was checked
The DermaFocus editorial team organized the reviews and research papers, and they were not supervised by medical professionals. This article does not constitute a medical diagnosis or recommendation for treatment, so please consult with a medical professional to determine whether and how to perform the procedure.
- Reviews: Among the 14,920 reviews of Gangnam Unni Rejuran, up to 1,000 each of Healer, Rejuran I, and HB Plus (all 865 for HB Plus) were classified among the 14,920 reviews with a body length of 40 characters or more, and 500 randomly selected among the 4,579 reviews of Babitalk Rejuran, for a total of 3,365 (as of October 7, 2026). Among them, 3,004 cases whose products are Healer, Ai, and HB are the subject of this article.
- Analysis standard: The effect ratio is based on 950 cases using the effect, the degree of pain is 1,362 cases, the number of cases is 810 cases, and the period of injection bumps is based on 215 cases.
- Study: 5 PN injection studies from PubMed. There is 1 review, 3 half-face comparisons, and 1 expert opinion, and only the abstracts were checked. The clinical paper marked as withdrawn in 2016 was not used as evidence.
- Price: Gangnam Unni sales price as of October 7, 2026 (including VAT, excluding first visit, experience, event, sedation and package products). Only the configurations where there were three or more locations and were comparable with the same capacity were averaged.
- Limitations: 99% of reviews were written within 1 month after the procedure. The number of reviews for each product is the result of a sample design, so it is not a percentage of use, and the Rejuran I has different concerns than the healer because it is a review of the eye area. I did not write about the pain reduction rate of HB because it varies from clinic to clinic and article to article.
- Personal Information: The original text of the review, the author, and the name of the clinic are not included.
Frequently Asked Questions
How do Rejuran Healer, Rejuran I and Rejuran HB differ?
In the reviews, the area and pain were different. Healers had many reviews of 2cc or 4cc on the entire face, 67% of Rejuran I had reviews on the eye area, and 4% of HB said that it was quite painful, which was much less than healers (24%) and Rejuran I (25%). The positive-review rate was 94% for Healer, 90% for HB, and 80% for Rejuran I, and the same 1cc published price was approximately 146,000 won, 173,000 won, and 157,000 won.
How much does Rejuran Healer hurt?
Of the 475 reviews that wrote about the pain level, 24% said it was quite painful, 33% said it was bearable, and 43% said it barely hurt. There are 180 reviews of sedation, so the influence of the anesthesia method is mixed.
Does Rejuran HB hurt less than healer?
It was like that in the review. Of the 492 HB reviews, 4% said it was quite painful, 61% said it was almost painful, and 24% and 43% of healers said it was very painful. The pain reduction rate varies from 50% to 70% in each article, so it is shown as a percentage of the reviews.
Can I take Rejuran I only for the eye area?
In the reviews, the eye area was 627 out of 938 (67%), and wrinkles and dark circles were the main concerns. 64% of reviews mentioned bruising, 7.0% mentioned swelling, which was more than other products, and the average duration of injection bumps was 1.5 days.
How many times should I take Rejuran?
The average number of reviews was 2.1 for Healer, 2.1 for Ai, and 2.0 for HB, and the interval was 5.5 to 6.0 weeks. The healer said that 96% of patients were good for the first time, 97% for the second time, and 87% for the third time or more, but since most of them were written immediately after the procedure, it is not the same standard as the recommended number of times.
How long do Rejuran injection bumps last?
It subsided within 2.0 days for Healer, 1.9 days for HB, and 1.5 days for Ai (70 cases, 91 cases, and 54 cases, respectively). Based on the article about bruising, 64% of Rejuran I, 53% of HB, and 50% of healers said that bruising occurred.
How much does Rejuran cost?
Based on the Gangnam Unni sales price, the average 1cc price was the highest for HB Plus at about 173,000 won, followed by Rejuran I at about 157,000 won and Healer at about 146,000 won. Healer 2cc is about 252,000 won, 4cc is about 430,000 won. The one-time price listed in the review is about 299,000 won for Healer, about 277,000 won for HB, and about 127,000 won for Rejuran I.
Does Rejuran work?
90% of the 950 reviews about its effectiveness said it was good. A review of 9 studies and 219 people also showed improvements in wrinkles, skin texture, and elasticity, and although side effects were mild, the study quality was low to medium.
How long do the effects of Rejuran last?
You can’t tell from the reviews. 99% of the 1,037 reviews were written within one month after the procedure. The paper also focuses on improvement immediately after the procedure rather than the maintenance period.
Sources and verification dates
- Lampridou S et al. Systematic review of the effect of polynucleotides in aesthetic medicine, J Cosmet Dermatol 2025 (PMID 39645667)(confirmed 2026-10-07): 9 studies, 219 people, results of improved wrinkles, skin texture, and elasticity, mild side effects, low to medium study quality
- Lee YJ et al. eye area PN filler and hyaluronic acid filler half face test, J Dermatolog Treat 2022 (PMID 32248707)(confirmed 2026-10-07): 27 people, 3 times at 2-week intervals, no difference in wrinkle scores, elasticity, moisture, and pore volume were higher in PN.
- Choi SY et al. eye area wrinkle PCL filler and PN filler half-face trial, J Cosmet Dermatol 2025 (PMID 39313949)(confirmed 2026-10-07): 218 patients, 12 weeks, PCL filler was not inferior, adverse reactions were minor
- Jeon W et al. Injection pain of ion-modulated PN filler half-face trial, Aesthetic Plast Surg 2026 (PMID 41361144)(confirmed 2026-10-07): 15 patients, pain 3.39 vs. 5.04, injection bumps 13.3% vs. 56.7%
- Rho NK et al. Expert opinion on evidence-based application of polynucleotides, Clin Cosmet Investig Dermatol 2026 (PMID 41939258)(confirmed 2026-10-07): 4 indications, no reports of granulomas and vascular occlusions, limited evidence.
- Gangnam Unni sales price (confirmed on 2026-10-07): Rejuran healer 2,405 cases, Rejuran I Rejuran 1,238 cases, Rejuran HB 891 events, same capacity configuration, VAT included, clinic name not listed
- Gangnam Unni review and Babitalk review (platform review, confirmed 2026-10-07): Based on sample classification of 3,365 Rejuran reviews. The original text of the review is not included.
Editorial responsibility and relationships
DermaFocus has no advertising, contract, or affiliation with any of the clinics or manufacturers mentioned in this article, and has not received any money or sponsorship. This article is a compilation of information needed to select a procedure and does not replace a personal diagnosis or treatment plan.